替吡法尼是一种有效的,特异性的法尼基转移酶(FTase) 抑制剂,IC50 值为 0.6 nM,法尼基转移酶抑制剂通过抑制CAAX尾部基序的烯丙基化来阻断法尼基转移酶的活性,这最终阻止Ras结合到膜上,使其失去活性.
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≥98% CAS No.:41851-59-6 -
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