艾拉莫德(T-614)是COX-2抑制剂,能抑制IL-1,IL-6,IL-8和肿瘤坏死因子的产生,是一种抗炎小分子药物,与甲氨喋呤一起用于治疗类风湿性关节炎.生物靶点尚不清楚,但它可以阻止NF-κB的激活,随后选择性地抑制COX-2和几种炎症.
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