托格列净是SGLT2高效选择性抑制剂,对人源、大鼠和小鼠SGLT2的Ki值分别为2.9、14.9和6.4nM,是治疗糖尿病的一种实验性药物,是亚型钠葡萄糖转运蛋白抑制剂（SGLT2）,这是负责至少百分之九十的葡萄糖重吸收在肾脏中.
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