罗替戈汀是多巴胺受体纯激动剂,是 5-HT1A receptor 的部分激动剂,以及 α2B-adrenergic receptor 的拮抗剂,Ki 值分别为 0.71 nM (dopamine D3 receptor),4-15 nM (D2,D5,D4 receptors),83 nM (dopamine D1 receptor),是治疗帕金森病（PD）和不宁腿综合征（RLS）的非麦角碱类药物的多巴胺激动剂.
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