齐泊腾坦是口服活性的内皮素A（ETA）受体特异性拮抗剂,IC50为21nM.齐泊腾坦是AstraZeneca开发的抗癌候选药物.齐泊腾坦被FDA批准用于治疗前列腺癌的快速跟踪状态.齐泊腾坦在乳腺癌、结直肠癌、非小细胞肺癌、卵巢癌、硬皮病相关肾脏病、骨转移和心力衰竭的临床试验中也有研究.
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