普马司他是一种广谱基质金属蛋白酶(MMP)抑制剂, 对 MMP-1,MMP-3 和 MMP-9 的 IC50 值分别为 79, 6.3 和 5.0 nM,抑制这些MMP是否能够通过防止MMP降解细胞外基质蛋白和血管生成来阻断肿瘤转移.
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