阿西替尼是一种 VEGFR 抑制剂,高浓度时也抑制 PDGFR,作用于 VEGFR1,VEGFR2,VEGFR3 和 PDGFRβ,IC50 分别为 0.1 nM,0.2 nM,0.1-0.3 nM 和 1.6 nM,是一种小分子酪氨酸激酶抑制剂.
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