菲尔替尼是一种选择性的 JAK 抑制剂,能够有效抑制 JAK1,JAK2,JAK3 和 TYK2 的活性,IC50 值分别为 10 nM,28 nM,810 nM 和 116 nM,是治疗类风湿性关节炎（RA）和克罗恩氏病的药物.
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