雷美替胺是高效选择性的melatonin受体激动剂,结合人melatonin1和melatonin2受体的Ki值分别为14 和112 pM,是一种睡眠剂,选择性地与视交叉上核(SCN)中的MT1和MT2受体结合,而不是与GABAA受体结合,例如与唑吡坦等药物结合.
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